The lecture purpose is to acquaint students with the hygienic characteristic of chemical production factors and measures of preventive maintenance of their harmful influence on an organism of the working. The general hygienic characteristic of chemical factors of industrial environment of common toxic action is given: concept, ways of receipt to an organism, biotransformation in an organism, deducing from an organism, classification by danger degree, and possible consequences of preventive maintenance sharp, subsharp, and chronic poisonings